By Sumaira Z. Aasi, David J. Leffell, Rossitza Z. Lazova
Mohs surgical procedure is microscopically managed surgical procedure used to regard universal different types of pores and skin melanoma and allows the removing of a pores and skin melanoma with a really slender surgical margin and a excessive healing expense. besides the fact that, for these concerned with the Mohs method, it really is severe to appreciate the optimum education and interpretation of frozen sections.
Complete with hundreds and hundreds of excessive solution figures, Atlas of useful Mohs Histopathology is written by means of best specialists within the box and discusses every little thing from general dermis histology and infrequent tumors to pitfalls and incidental findings. Dermatologic surgeons, Mohs cutaneous surgeons, dermatopathologists and pathologists alike will locate this booklet to be a entire and imperative reference.
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Additional resources for Atlas of Practical Mohs Histopathology
No clefts between the tumor aggregates and the surrounding stroma. Desmoplastic Trichoepithelioma 1. 2. 3. 4. 5. Well-circumscribed, symmetric plate-like growth pattern confined to the upper or mid dermis. , infundibular cysts, trichohyaline granules, etc. Presence of calcifications. Absence of clefts around epithelial tumor aggregates and the surrounding stroma. Dense collagenous stroma around tumor aggregates. Microcystic Adnexal Carcinoma 1. Larger, asymmetric, poorly circumscribed, and deeply infiltrative neoplasm that often involves the subcutaneous fat and skeletal muscle.
They are larger, ovoid in shape, and with more abundant eosinophilic cytoplasm (arrow) 3 a b Basal Cell Carcinoma Basal Cell Carcinoma Fig. 9 Basal cell carcinoma: (a) Basal cell carcinoma with large areas of necrosis in the center of the aggregates (arrows). (b) Basal cell carcinoma with neoplastic cells that demonstrate a reticulated pattern 33 a b 34 Fig. 10 Basal cell carcinoma: (a–c) This example illustrates that the diagnosis of BCC is most easily made by evaluating the overall growth pattern and architecture of the tumor.
3. Because of the increased possibility of perineural invasion associated with infiltrative BCC, the surgeon should examine areas of tumor involvement carefully. 4. Nerves within the area of the carcinoma and particularly at its periphery should be scrutinized to identify this subtle phenomenon. 5. It is a common practice to examine multiple sections when there is dense perineural inflammation to exclude the possibility of perineural invasion. Fig. 1 (a, b) Infiltrative basal cell carcinoma: poorly circumscribed and deeply infiltrative tumor aggregates diminishing in size from superficial to deep dermis a b 50 Fig.
Atlas of Practical Mohs Histopathology by Sumaira Z. Aasi, David J. Leffell, Rossitza Z. Lazova